Mutation: Substitution

Mutations: Substitution

* Substitution is a mutation that occurs when a base(s) of a nucleotide is exchanged for another.
* This can change the coding of the entire amino acid sequence.
* This is considered one of the more least deadly mutations.
* Substitution Mutation can have a variety of effects. Nothing could happen from substitution because it codes for the same protein or it could cause either an early stop or no stop at all.
* A premature stop badly affects the formation of proteins.

Reflection:
In summary, Substitution Mutation can either do nothing to your body or change it completely. Your body can stop making proteins if it causes a premature stop in the coding sequence which surprised me when we were learning about this. It's also kind of easier to determine what kind of mutation happened with substitution because you don't have to count how many nucleotides there are in the sequence. You just have to find out which nucleotide(s) were changed as you read through it. I didn't know about any of this before and when we were learning about mutations in general I didn't think it affected the proteins in the body at all. I though it gave you stuff like six arms or super powers and not give you disease like cancer. This objective was interesting because I figured out why some mutations were less deadly than others. I don't know how this can be applied outside of biology but it could maybe help doctors determine stuff.

"Genetic Code Mutations." SparkNotes, www.sparknotes.com/biology/molecular/geneticcode/section3.rhtml. Accessed 13 Apr. 2017.