Mutations: ADDITION (INSERTION)
Important facts -
- Change in DNA sequence
- Changes the protein
- Makes wrong amino acids
- Frameshift mutation
- Also known as insertion
- Spontaneous mutations
In Depth -
There are three main types of mutation; addition, deletion, and substitution. Most of the time, mutations are completely random. Mutations happen when the wrong amino acid is created during replication. Mutations such as insertion or deletion change the number of amino acids causing what is known as a frameshift. These frameshift mutations change everything after them. Substitution mutations are not as severe. Mutations are the cause of most cancers and more medical complications.
Example:
Original Strand: ATC TGC GCA TAG
Replicated Strand: TAG ACC GCG TAT G
As you can see during this replication, there was a nitrogen base added in the middle of the strand. This caused the wrong acid and wrong protein to be produced and also changed not one amino acid, but all of the acids that followed behind it.
Citations
"DNA Mutations | Genetics | Biology". YouTube. N.p., 2017. Web. 5 May 2017.
"Islaslab - Mutation". Islaslab.wikispaces.com. N.p., 2017. Web. 5 May 2017.
This has very interesting pictures. What diseases can be caused by addition?
ReplyDeleteAn addition mutation can cause non-functioning proteins
DeleteWhich mutation is the most common?
ReplyDeleteYou did a good job of simplifying the information and it was very easy to read and understand! Also well organized and I enjoyed the video.
ReplyDelete